Xin Wu, MD, Texas A&M Health Science Center

 

Publications:

Citation (total >1981. Impact index (h-index) = 20 and i10-index = 25 in google scholar, https://scholar.google.com/citations?user=cq9jzLoAAAAJ&hl=en)) based on Google Scholar on Nov. 2019.

Papers after 1998 with ‘PDF’ files: http://people.tamu.edu/~xinwu/paper/

1.      Wu X and Chen X. Correlative analysis between the mark of medical physiology and mark of other medical courses. Journal of Education and Research Nantong (Tong Yi Jiao Yan) 4: 49-51, 1989.

2.      Wu X, et al. Views on the central transference of biological medicine from the Nobel Prize in Physiology or/and Medicine. Journal of Education and Research Nantong (Tong Yi Jiao Yan) 7:52-55, 1991.

3.      Shen H, Wu X. Evaluation of biological field by simplified psychological stress in a mice model and its antagonism against "ocular stress." Acta Academiae Medicinae Nantong 12(4): 293-297, 1992.

4.      Huang WQ, Xu HD, Wu X, et al. Role of the central alpha-receptors in the modulation of carotid sinus reflex of rats. Acta Physiologica Sinica (Shen Li Xue Bao), 44(6) 556-561, 1992.

5.      Wu X. Ion channels and ion currents in ventricular muscles. Acta Academiae Medicinae Nantong 13(1): 89-92, 1993.

6.      Wu X, Huang WQ, Yu ZM. Histamine-induced early afterdepolarizations and triggered activity in guinea pig papillary muscles. Chinese Journal of Applied Physiology 9(3): 236-240, 1993.

7.      Huang QW, Wu X, et al. Electrophysiological study on histamine-induced arrhythmias in guinea pig papillary muscles. Acta Academiae Medicinae Suzhou 14(3): 180-187, 1994.

8.      Wu X, Huang WQ, Zhang QQ and Yu ZM. Effects of histamine on electrophysiological properties and triggered activity in guinea pig papillary muscles. Methods and Findings in Experimental and Clinical Pharmacology 16(8): 583-587, 1994.

9.      Wu X, Huang WQ and Yu ZM. Specific antigen-induced early afterdepolarizations and triggered activity in sensitized guinea-pig papillary muscles. Chinese Journal of Applied Physiology 11: 51-54, 1995.

10.  Wu X, Teng AF, Huang WQ and Yu ZM. Role of histamine receptors in the genesis of delayed afterdepolarizations induced by specific antigen in sensitized guinea-pig papillary muscles. Chinese Journal of Applied Physiology 12: 178-182, 1996.

11.  Wu X and Davis MJ. The treatment of acute coronary syndromes. The Circulation Frontier 2(1): 27-38, 1998.

12.  Wu X, Mogford JE, Davis GE, Platts S, Meininger GA and Davis MJ. Modulation of calcium current in arteriolar smooth muscle by avb3 and a5b1 integrin ligands. Journal of Cell Biology 143(1): 241-252, 1998. (impact factor: 12.78 in 1998 by SCI; time cited by other papers: 208)

13.  Davis MJ, Wu X, Nurkiewicz TR, Kawasaki J, Davis GE, Hill MA, Meininger GA. Integrins and mechanotransduction of the vascular myogenic response. Am J Physiol, 280: H1427-1433, 2001 (cited by 192).

14.  Wu X and Davis MJ. Characterization of stretch activated cation current in vascular smooth muscle cells. American Journal of Physiology 280: H1751-1760, 2001. (cited by 91)

15.  Davis MJ, Wu X, Nurkiewicz TR, Kawasaki J, Gui P, Hill MA, Wilson E. Regulation of ion channels by protein tyrosine phosphorylation. Am J Physiol, 281: H1835, 2001. (Impact factor: 2.74; cited by 187).

16.  Wu X, Davis GE, Meininger GA, Wilson E, Davis MJ. Regulation of the L-type calcium channel by a5b1 integrin requires signaling between focal adhesion proteins. J Biol Chem 276:30285, 2001. (impact factor: 7.66; cited by 183)

17.  Davis MJ, Wu X, Nurkiewicz TR, Gui PC, Kawasaki J, Hill MA, Wilson E. Regulation of ion channels by integrins. Cell Biochemistry and Biophysics, 36:41-66, 2002. (cited by 74).

18.  Waitkus-Edwards KR, Martinez-Lemus LA, Wu X, Trzeciakowski JP, Davis MJ, Davis GE and Meininger GA. a4b1 integrin activation of L-type calcium channels in vascular smooth muscle causes arteriole vasoconstriction. Circ Res, 90:473-480, 2002. (Featured in Editorial and on Cover)  (impact factor: 8.28; cited by 121)

19.   Marinez-Lemus LA, Wu X, Wilson E, Hill MA, Davis GE, Davis MJ, Meininger GA.  Integrins as unique receptors for vascular control. J Vasc Res, 40:211-233, 2003. (impact factor: 3.58; cited by 164).

20.  Gui P, Wu X, Ling S, Stotz SC, Winkfein RJ, Wilson E, Davis GE, Braun AP, Zamponi GW, Davis MJ. Integrin receptor activation triggers converging regulation of Cav1.2 calcium channels by c-Src and PKA pathways. J Biol Chem, 281:14015-25, 2006 (cited by 100).

21.  Qamirani E, Razavi HM, Wu X, Davis MJ, Kuo L, Hein TW. Sodium azide dilates coronary arterioles via activation of inward rectifier K+ channels and Na+-K+-ATPase. Am J Physiol 290: H1617-H1623, 2006. (impact factor: 3.7, citied by 16)

22.  Wu X, Yang Y, Gui P, Sohma Y, Meininger GA, Davis GE, Braun AP and Davis MJ. Potentiation of large conductance, Ca2+-activated K+ (BK) channels by alpha5beta1 integrin activation in arteriolar smooth muscle. J Physiol. 586:1699-713, 2008 (impact factor: 4.3; cited by 58).

23.  Wu X, Sun Z, Foskett A, Trzeciakowski JP, Meininger GA and Muthuchamy M. Cardiomyocyte contractile status is associated with differences in fibronectin and integrin interactions. Am J Physiol, 298: H2071-H2081, 2010 (impact factor: 3.88. cited by 50).

24.  Yang Y, Wu X, Wu J, Sheng JZ, Ling S, Braun AP, George E. Davis GE, Davis MJ. a5b1 integrin activation increases BK channel current and Ca2+ sensitivity through c-Src mediated channel phosphorylation. J Biol Chem, 285:131-141, 2010 (impact factor: 5.3, cited by 39).

25.  Gui P, Chao JT, Wu X, Yang Y, Davis GE, Davis MJ. Coordinated regulation of vascular K+ and Ca2+ channels by integrin signaling. Adv Exp Med Biol. 674:69-79, 2010 (cited by 27).

26.  Wu X, Chakraborty S, Heaps CL, Davis MJ, Meininger GA and Muthuchamy M. Fibronectin increases the cardiac contractility of mouse ventricle via alpha (5) beta (1) integrin. Journal of Molecular and Cellular Cardiology, 50:203-213, 2011 (impact factor: 5.17, cited by 9).

27.  Wu X and Reddy DS. Integrins as receptor targets for neurological disorders. Pharmacology & Therapeutics, 134:68, 2012 (Impact Factor: 9.33 in the past 5 years averaged. Cited by 99)

28.  Wu X, Sun Z and Meininger GA, and Muthuchamy M. Application of Atomic Force Microscopy Measurements on Cardiovascular Cells. Methods Mol Biol. 843:7229-44, 2012. (Impact Factor:1.71 in 2010, cited by 12).

29.  Zawieja SD, Wang W, Wu X, Nepiyushchikh Z, Zawieja DC, and Muthuchamy M. Impairments in the intrinsic contractility of mesenteric collecting lymphatics in a metabolic syndrome rat model. Am J Physiol Heart Circ Physiol, 302:H643-53, 2012. (Impact Factor:3.63, cited by 68).

30.  Tangney JR, Chuang JS, Janssen MS, Krishnamurthy A, Liao P, Hoshijima M, Wu X, Meininger GA, Muthuchamy M, Zemljic-Harpf A, Ross RS, Frank LR, McCulloch AD, Omens JH. Novel role for vinculin in ventricular myocyte mechanics and dysfunction. Biophys J. 2013; 104: 1623-33 (My works included AFM, gene expression & immunocytochemistry in cardiomyocytes in Fig.4 and Fig S2 & Fig S3. Impact Factor:3.83, cited by 28).

31.  Wu X, Carver CM, Gangisetty O, Reddy DS. Estrous cycle regulation of extrasynaptic δ-containing GABAA receptor-mediated tonic inhibition and limbic epileptogenesis. J Pharmacol Exp Ther, 2013, 346:146-160. (Impact factor: 3.85, cited by 58).

32.  Carver CM, Wu X, Gangisetty O, and Reddy DS. Perimenstrual regulation of extrasynaptic δ-containing GABAA receptors mediating tonic inhibition and neurosteroid sensitivity. J Neurosci, 2014, 34:14181-14197 (impact factor: 6.75, cited by 48).

33.  Tong CW, Wu X, Liu Y, Rosas PC, Sadayyappan S, Hudmon A, Muthuchamy M, Powers PA, Valdivia HH, Moss RL. Phosphoregulation of cardiac inotropy via myosin binding protein-C during increased pacing frequency or β1-adrenergic stimulation. Circulation:Heart Failure, 2015, 8:605-618. (Featured in Editorial)   (Impact factor: 5.89, cited by 34).

34.  Golub VM, Brewer J, Wu X, Kuruba R, Short J, Manchi M, Swonke M, Younus I, and Reddy DS. Neurostereology protocol for unbiased quantification of neuronal injury and neurodegeneration. Frontiers in Aging Neuroscience, 2015, 7:196. doi: 10.3389/fnagi.2015.00196. (Impact factor: 4.00, cited by 38).

35.  Wu X, Muthuchamy M, Reddy DS. Application of atomic force microscopy for measurements of membrane plasticity and extracellular interactions in dentate gyrus granule cells in chronic epilepsy. Frontiers in Aging Neuroscience, 2016, 8:88. doi: 10.3389/fnagi.2016.00088. (Impact factor: 4.00, cited by 15).

36.  Reddy DS, Gangisetty O, Wu X. PR-Independent Neurosteroid Regulation of α2-GABA-A Receptors mRNA in the Hippocampus Subfields. Brain Research, 2017, 1659:142-147. doi: 10.1016/j.brainres.2017.01.030. Epub 2017 Jan 28. (Impact factor: 3.13, cited by 10)

37.  Wu X, Muthuchamy M, Reddy DS. Atomic force microscopy investigations of fibronectin and α5β1-integrin signaling in neuroplasticity and seizure susceptibility in experimental epilepsy. Epilepsy Research, 2017, 138:71-80. doi: 10.1016/j.eplepsyres.2017.10.013. (Impact factor: 2.5, cited by 5)

38.  Wu X, Kuruba R, Reddy DS.  Midazolam-Resistant Seizures and Brain Injury following Acute Intoxication of Diisopropylfluorophosphate, an Organophosphate Pesticide and Surrogate for Nerve Agents. J Pharmacol Exp Ther. 2018, 367(2):302-321. doi: 10.1124/jpet.117.247106.  PMID: 30115757. (Impact factor: 3.87, Cited by 17)

39.  Reddy DS, Wu X, Golub VM, Dashwood WM, Dashwood RH. Measuring Histone Deacetylase Inhibition in the Brain. Curr Protoc Pharmacol. 2018 Jun;81(1):e41. doi: 10.1002/cpph.41. Epub 2018 Jun 7. PMID: 29927058. (Impact factor: 1.03, cited by 6)

40.  Kuruba R, Wu X, Reddy DS. Benzodiazepine-refractory status epilepticus, neuroinflammation, and interneuron neurodegeneration after acute organophosphate intoxication. Biochim Biophys Acta. 2018 Sep;1864(9 Pt B):2845-2858. doi: 10.1016/j.bbadis.2018.05.016. Epub 2018 May 23. PMID: 29802961. (Impact factor: 3.68, 5-Year Impact Factor: 4.81, Cited by 16)

41.  Reddy DS, Carver CM, Bryan C and Wu X. Extrasynaptic GABA-A receptor-mediated sex differences in the antiseizure activity of neurosteroids in status epilepticus and complex partial seizures. Epilepsia, 2019, 60(4):730-743. DOI: 10.1111/epi.14693. (Impact factor: 5.56, cited by 8)

42.  Reddy DS, Perumal D, Golub V, Habib A, Kuruba R and Wu X. Phenobarbital as alternate anticonvulsant for organophosphate-induced benzodiazepine refractory status epilepticus and neuronal injury.  Epilepsia Open, 5(2):198-212, DOI: 10.1002/epi4.12389.

43.  Reddy SD, Wu X, Kuruba R, Sridhar V, & Reddy DS. Magnetic resonance imaging analysis of long-term neuropathology after exposure to the nerve agent soman: correlation with histopathology and neurological dysfunction. Ann. N.Y. Acad. Sci., July 15, 2020. doi: 10.1111/nyas.14431. (Impact factor: 4.73)

 

Book Chapters:

1.      Wu X, et al. Application of Atomic Force Microscopy Measurements on Cardiovascular Cells. In: Cardiovascular Development: Methods and Protocols. Peng X and Antonyak MA eds. Humana Press, USA (Part of the Springer publishing group), 2012, (same as Methods Mol Biol. 843:229-44, 2012).

2.      Wu X, et al. Basic theory and application of computer in Physiology. In: Experimental Guide of Physiology, Teng AF, et al. (eds.), pp 17-22, Southeastern University Press, China, 1992.

3.      Wu X, et al. Computerized measure of strength-duration curve in the muscle. Experimental Guide of Physiology, Teng AF, et al., (eds.), pp 49-51, Southeastern University Press, China, 1992.

4.      Wu X. The regulation of cardiac output. In: Guide for Physiological Experiment, Teng AF, et al. (eds.), pp 64-66, Suzhou Medical College Press, China, 1988.

5.      Wu X. The measurement of human arterial blood pressure. In: Guide for Physiological Experiment, Teng AF, et al. (eds.), pp 67-68, Suzhou Medical College Press, China, 1988.

6.      Wu X. Physical diagnosis of heart sound. In: Guide for Physiological Experiment, Teng AF, et al. (eds.), pp 69-70, Suzhou Medical College Press, China, 1988.

7.      Wu X. Survey of microcirculation in animals. In: Guide for Physiological Experiment, Teng AF, et al. (eds.), pp 70-71, Suzhou Medical College Press, China, 1988.

 

Abstracts:

1.      Xin Wu, Min-Jung Park, Ramkumar Kuruba, Farida Sohrabji, and Doodipala Samba Reddy. The long-term epileptogenic impact of stroke in mature adult and reproductive senescent female rats. (A) American Epilepsy Society Annual Meeting, Dec. 2019. Abst #1.454. (B) Texas A&M Chapter of the Society for Neuroscience, Winter Symposium 2019, Dec. 2019

2.      Zaynab Garbe, Victoria Golub, Xin Wu, D. Samba Reddy. Epigenetic his tone deacetylase activity in mouse model of post-traumatic epilepsy. Research Day in 2019 Summer Research Program. Texas A&M Health Science Center, Bryan, TX, July 27, 2019.

3.      Pamela Horton, Wei Wang, Xin Wu, D Samba Reddy, Mariappan Muthuchamy. Remodeling of Meningeal Lymphatics and Cervical Lymph Node in Pilocarpine-Induced Mouse Epilepsy Model. Research Day in 2019 Summer Research Program. Texas A&M Health Science Center, Bryan, TX, July 27, 2019.

4.      Gianmarco Calderara, Victoria Golub, Xin Wu and D. Samba Reddy. Epigenetic attenuation of the long-term neuropatholgoical effects of acute organophosphate exposure in rats . (A) Research Day in 2019 Summer Research Program. Texas A&M Health Science Center, Bryan, TX, July 27, 2019. (B) LAUNCH Undergraduate Research Summer Poster Session, Texas A&M University, July 31, 2019.

5.      Perumal D, Golub V, Wu, X and Reddy DS. Effects of phenobarbital treatment for organophosphate-induced refractory status epilepticus and neuronal injury. (A) 24th Annual Graduate Research Symposium, Texas A&M Health Science Center, Bryan, April, 2019; (B) Texas A&M Institute For Neuroscience 11th Annual Symposium, Texas A&M University, College Station, April, 2019.

6.      Wu X, Kuruba R, and Reddy DS. Midazolam-Resistant Seizures and Brain Injury following Acute Intoxication of Diisopropylfluorophosphate, an Organophosphate Pesticide and Surrogate for Nerve Agents. American Epilepsy Society Annual Meeting, Dec. 2018. Abst #1.110.

7.      Kuruba R, Wu X, and Reddy DS. Benzodiazepine-Refractory Status Epilepticus, Neuroinflammation, and Interneuron Neurodegeneration after Acute Organophosphate Intoxication. American Epilepsy Society Annual Meeting, Dec. 2018. Abst #1.109.

8.      Bruggemann J, Reddy T, Golub V, Kuruba R, Wu X, and Reddy DS. Effect of the Microglia Inhibitor Sodium Butyrate or Ibudilast on Long-term Neuropathology after Acute Organophosphate Intoxication. (A) 23rd Annual Graduate Research Symposium, Texas A&M Health Science Center, Bryan, April, 2018; (B) Texas A&M Institute For Neuroscience 10th Annual Symposium, Texas A&M University, College Station, April, 2018.

9.      Reddy DS, Kuruba R, Wu X. Protective effect of neurosteroid-midazolam combination regimen in soman model in rats. Denver,CO: NIH CounterACT Network Research Symposium; June 13, 2018.

10.  Reddy DS, Andy Habib, Ramkumar Kuruba, Xin Wu. Efficacy of Phenobarbital for the Treatment of Organophosphate-Induced Refractory Status Epilepticus and Neuronal Injury.  2017 Annual Meeting of the American Epilepsy Society, Poster Session #:  2.024.

11.  Ramkumar Kuruba, Xin Wu, Andy Habib, Victoria Golub and D. Samba Reddy. Efficacy Of Phenobarbital For The Treatment Of Organophosphate-Induced Refractory Status Epilepticus And Neuronal Injury. Texas A&M Chapter of the Society for Neuroscience Annual Symposium 2017, 47.U.B., Dec. 6, 2017.

12.  Sarah Elmer, Bryan Clossen, Victoria Golub, Xin Wu and D. Samba Reddy. Effect Of Neurosteroid Therapy On Neurodegeneration In The Mouse Pilocarpine Model Of Chronic Epilepsy.  Texas A&M Chapter of the Society for Neuroscience Annual Symposium 2017, 2.U.B., Dec. 6, 2017.

13.  Kancharla S, Kuruba R, Wu, X (mentor) and Reddy DS. Ganaxolone reduces electrophysiological high-frequency oscillations (HFOs) in a rat model of temporal lobe epilepsy. 2017 Summer Research Program. Texas A&M Health Science Center, Bryan, TX, July. 2017.

14.  Andy Habib, Xin Wu, Victoria Golub, Ramkumar Kuruba, D. Samba Reddy. Protective effects of phenobarbital against the organophosphate DFP-induced refractory status epilepticus and neuronal injury in rats. (A) 22st Annual Graduate Research Symposium, Texas A&M Health Science Center, Bryan, April 21, 2017; (B) Texas A&M Institute For Neuroscience 9th Annual Symposium, Texas A&M University, College Station, April 28, 2017.

15.  Xin Wu, Bryan Clossen, Mariappan Muthuchamy, and Doodipala Reddy. Fibronectin Modulates Neuroplasticity in Hippocampal Neurons via Alpha5Beta1-Integrins in Epilepsy. 2016 Annual Meeting of the American Epilepsy Society, Poster Session #:  1.012.

16.  Xin Wu, Bryan Clossen, Mariappan Muthuchamy, and Doodipala Reddy. Role of extracellular matrix protein fibronectin-integrin signaling in the hippocampal dentate gyrus in epilepsy. FASEB J, April 2016, 30:705.2. (cited by 1).

17.  Xin Wu, Shu-Hui-Chuang, Mariappan Muthuchamy, D. Samba Reddy. Fibronectin-integrin modulation of neuroplasticity in the hippocampal dentate gyrus granule cells in epilepsy. (A) Texas A&M Institute For Neuroscience 8th Annual Symposium, Texas A&M University, College Station, April 15, 2016. (B) 21st Annual Graduate Research Symposium, Texas A&M Health Science Center, Bryan, April 22, 2016; (C) College of Pharmacy Research Colloquium, Texas A&M Health Science Center, College Station, June 3-4, 2016.

18.  Hoang D, Dunlap V, Clossen B, Wu X, and Reddy DS. Quantification of neurodegeneration in a mouse pilocarpine model of chronic epilepsy. (A) 2015 Summer Research Program. Texas A&M Health Science Center, Bryan, TX, Aug. 2015; (B) TBSI Symposium, Annenberg Conference Center - George Bush Presidential Library. The Texas Brain and Spine Institute. College Station, TX. Sept.  2015.

19.  Madhavi K, Abbas D, Wu X, Clossen B, and Reddy DS. LC-MS/MS Analysis of Brain Neurosteroid Levels in Plasma and Brain Samples. 20th Annual Graduate Student Organization Research Symposium, April 17, 2015.

20.  Iype S, Patel R, Patil G, Kuruba R, Wu X and Reddy DS. Benzodiazepines fail to stop the progression of epilepsy development: A video-EEG analysis of DFP-treated rats. (A) 7th Annual Symposium, Texas A&M Institute for Neuroscience, March, 2015; (B) 20th Annual Graduate Student Organization Research Symposium, April 17, 2015.

21.  Dunlap V, Brewer J, Short J, Swonke M, Younus I, Raju D, Kuruba R, Wu X and Reddy DS. An Optimized Brain Stereology Protocol for Neuron Counting.  (A) 7th Annual Symposium, Texas A&M Institute for Neuroscience, March, 2015; (B) 20th Annual Graduate Student Organization Research Symposium, April 17, 2015.

22.  Wu X, Kuruba R, and Reddy DS. Midazolam refractory seizures and brain injury following acute organophosphate intoxication. (A) American Epilepsy Society Annual Meeting, DeDecc. 2014. Abst #1.031.  (B) 7th Annual Symposium, Texas A&M Institute for Neuroscience, March, 2015. (cited:2).

23.  Kuruba R, Wu X, and Reddy DS. Benzodiazepine Resistant Status Epilepticus and Brain Injury in DFP Model of OP Intoxication. (A) American Epilepsy Society Annual Meeting, Dec. 2014. Abst #1.029. (B) 7th Annual Symposium, Texas A&M Institute for Neuroscience, March, 2015 (First place in the poster section).(cited:2).

24.  Carver CM, Wu X, Gangisetty O and Reddy DS. Perimenstrual Upregulation of δ-Subunit Extrasynaptic GABA-A Receptors Mediating Tonic Inhibition and Neurosteroid Sensitivity. (A) American Epilepsy Society Annual Meeting, Dec. 2014. (B) 7th Annual Symposium, Texas A&M Institute for Neuroscience, March, 2015.

25.  Abbas D, Wu X, Clossen B, and Reddy DS. LC-MS/MS Analysis of Brain Neurosteroid Levels in a Mouse Epilepsy Model. (A) 2014 Summer Research Program. Texas A&M Health Science Center, Bryan, TX, Aug. 2014. (B) 7th Annual Symposium, Texas A&M Institute for Neuroscience, March, 2015.

26.  Younus I, Short J, Dunlap V, R. Kuruba R, Wu X, and Reddy DS. Quantification of Neuroinflammation by Area Fractionation Method in Epilepsy Brain Injury Models. (A) 2014 Summer Research Program. Texas A&M Health Science Center, Bryan, TX, Aug. 2014. (B) 7th Annual Symposium, Texas A&M Institute for Neuroscience, March, 2015.

27.  Short J, Brewer J, Dunlap V, Swonke M, Younus I, Raju D, Kuruba R, Wu X and Reddy DS. An Optimized Brain Stereology Protocol for Neuron Counting. 2014 Summer Research Program. Texas A&M Health Science Center, Bryan, TX, Aug. 2014.

28.  Reddy DS, Kuruba R and Wu X. Time–dependent diazepam insensitivity in the DFP model of status epilepticus. American Epilepsy Society Annual Meeting. Abs# 1.045, 2013

29.  Wu X, Sun Z, Ross RS, Meininger GA, Muthuchamy M. Fibronectin-Induced Mechanotransduction Mediated by alpha (5) beta (1) Integrin Requires intracellular signaling in Mouse Cardiomyocytes. 4th Cardiovascular Research Symposium at Texas A&M Health Science Center, Temple, Texas 2013.

30.  Raju D, Ceiker R, Brewer J, Kuruba R, Wu X, Reddy DS. Stereological quantification of neurodegeneration in a rat model of epilepsy. Summer research program, Health professional education building, Bryan, TX, Aug.,  2013.

31.  Reddy DS, Kuruba, R and Wu X.  Comparative characterization of organophosphate-intoxication and lithium-pilocarpine models of refractory status epilepticus and neurodegeneration. (A) Proceedings of the 4th Biennial North American Epilepsy Congress, American Epilepsy Society; San Diego. December 2–6, 2012; AES Annual Meeting Abstract 2.028. (B) Society for Neuroscience Texas A&M Chapter. Annual Poster Presentation (name listing may different), Texas A&M University, College Station, TX, Dec, 2012.

32.  Muthuchamy M, Chakraborty, Wu X, Sarin V and Heaps CL. Exercise-induced changes in mechanotransduction improve myocardial function in a porcine model of chronic occlusion. Circulation. 2012, 126: 2012-SS-A-19552 (<30% acceptance rate, Impact factor = 14.429).

33.  Wu X, Carver C, Gangisetty O, Murchison D, Griffith WH, Reddy, DS. Menstrual cycle regulation of extrasynaptic δ-containing GABA-A receptor plasticity and tonic inhibition in the hippocampus subfields. (A) TBSI Symposium, Annenberg Conference Center - George Bush Presidential Library. The Texas Brain and Spine Institute. College Station, TX. Sept.  2012; (B) Neuroscience 2012 (name listing may different), Society for Neuroscience, New Orleans, LA. Abs# 247.09, Oct., 2012. (C) Society for Neuroscience Texas A&M Chapter. Annual Poster Presentation (name listing may different), Texas A&M University, College Station, TX, Dec, 2012.

34.  Carver C, Gangisetty O, Wu X, Reddy, DS. Perimenstrual neurosteroid withdrawal induces upregulation of neurosteroid-sensitive δ-containing GABAA receptors in the hippocampus subfields. (A) TBSI Symposium, Annenberg Conference Center - George Bush Presidential Library. The Texas Brain and Spine Institute. College Station, TX. Sept.  2012; (B) Neuroscience 2012 (name listing may different), Society for Neuroscience, New Orleans, LA. Abs#: 247-10. Oct., 2012; (C) Society for Neuroscience Texas A&M Chapter. Annual Poster Presentation (name listing may different), Texas A&M University, College Station, TX, Dec, 2012.

35.  Reddy DS, Kuruba R, and Wu X (2012). Poster presentation. A neurosteroid-based novel treatment for OP-intoxication. 6th Annual Counter ACT Network Research Symposium 2012 (San Francisco, CA).

36.  Wu X, Muthuchamy M, Reddy DS. Atomic force microscopy study of ECM-integrin modulation of neuroplasticity in the hippocampal dentate granule cells in epilepsy. The FASEB Journal. 2012, 26:672.8. The Fourth Annual Faculty of Neuroscience Symposium, Texas A&M Health Science Center, April 2012.(cited:1)

37.  Carver C, Wu X, Murchison D, Griffith WH, Reddy, DS. Ovarian cycle-related effects of neurosteroids on GABA-A receptor-mediated phasic and tonic currents in the hippocampus. FASEB Journal, 2012, 26:1048.3. The Fourth Annual Faculty of Neuroscience Symposium, Texas A&M Health Science Center, April 2012.

38.  Zawieja SD, Wu X, Chakraborty S and Muthuchamy M. TNF-α mediated regulation of myosin light chain 20 phosphorylation in lymphatic muscle. The FASEB Journal. 2012, 26: 677.6.  The 17th Annual College of Medicine Graduate Student Organization Student Research Symposium. May 2012.

39.  Carver C, Gangisetty O, Wu X and Reddy DS. Plasticity and function of δ-containing GABA-A receptors in a perimenstrual model of neurosteroid withdrawal. The Fourth Annual Faculty of Neuroscience Symposium, Texas A&M Health Science Center, April 2012. The 17th Annual College of Medicine Graduate Student Organization Student Research Symposium. May 2012 (The 3rd Place on Poster presentation).

40.  Tong CWC, Abdalla, MI,  Wu X,  Liu Y, Muthuchamy M, Moss RL. Lack of cardiac myosin binding protein-c phosphorylation is a model of heart failure with preserved ejection fraction. J Am Coll Cardiol. 2012;59(13s1):E860-E860 (cited by 1).

41.  Wu X, Gui PC, Li J, Balasubramanian B, Braun AP, Zamponi GW, Heaps CL, Murchison D, Griffith WH, Meininger GA, Muthuchamy M and Davis MJ. Regulation of cardiac and neuronal L-type calcium channels by α5β1 integrin activation requires protein phosphorylation. The 16th Annual College of Medicine Graduate Student Organization Student Research Symposium. May 2011.

42.  Wu X, Meininger GA,  Muthuchamy M. Feedback mechanisms linking regulation of ECM-integrin adhesion with myofilament activation. Symposium presented by Dr. Muthuchamy on Tuesday in Experimental Biology 2011, Washington, DC, April 9-13, 2011.

43.  Zawieja SD, Wang W, Nepiyushchikh Z, Wu X, Zawieja DC, and Muthuchamy M. Rat mesenteric lymphatics undergo remodeling and have altered contractility and calcium sensitivity in a model of metabolic syndrome. FASEB J, March 17, 2011 25:632.2. The 16th Annual College of Medicine Graduate Student Organization Student Research Symposium. May 2011.

44.  Reddy DS, Gangisetty O and Wu X. Ovarian cycle-related changes in expression and function of extrasynaptic GABA-A receptors in the hippocampus subfields. Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, Nov. 2011. Program#/Poster#: 338.07/C44.

45.  Wu X, Murchison D, Griffith W and Reddy DS. Ovarian cycle-related effects of neurosteroids on extrasynaptic GABA-A receptor-mediated tonic inhibition in the hippocampus. Annual Neuroscience Symposium. The Texas Brain and Spine Institute. Bryan, TX 2011.

46.  Carver C, Wu X, and Reddy DS. Ovarian cycle-related effects of neurosteroids and benzodiazepines on GABA-A receptor-mediated whole-cell currents in the hippocampal neurons. Annual Neuroscience Symposium. The Texas Brain and Spine Institute. Bryan, TX 2011.

47.  Wu X, Carver C and Reddy DS. Ovarian Cycle-Related Neurosteroid Potentiation of GABAA Receptor Currents in Acutely Dissociated Hippocampal Neurons. The Third Annual Faculty of Neuroscience Symposium, Texas A&M Health Science Center, April 2011.

48.  Wu X, Sun Z, Ross RS, Meininger GA, Muthuchamy M. Fibronectin-Induced Mechanotransduction Mediated by alpha (5) beta (1) Integrin Requires Calcium and Vinculin in Mouse Cardiomyocytes. Circulation. 2010, 122: A19792 (<30% acceptance rate, Impact factor = 14.429, cited by 3).

49.  Tong CW, Wu X, Muthuchamy M, Sadayappan S, Hudmon A Valdivia HH, Moss RL. Frequency dependent phosphorylation of cardiac myosin binding protein-C mediates acceleration of myocardial relaxation to support normal diastolic function. Circulation. 2010, 122: A16507. (<30% acceptance rate, cited by 3)

50.  Wu X, Muthuchamy M, Moss RL and Tong CW. Loss of cardiac myosin binding protein-C phosphorylation mediated tuning of cross-bridge kinetics causes diastolic dysfunction. Texas A&M Health Science Center Research Symposium, November 11-12, 2010.

51.  Wu X, Gui PC, Li J, Balasubramanian B,  Braun AP, Zamponi GW, Heaps C, Murchison D, Griffith WH, Meininger GA, Muthuchamy M and Davis MJ.  Regulation of cardiac (Cav1.2a), smooth muscle (Cav1.2b) and neuronal (Cav1.2c) L-type calcium channels by a5b1 integrin activation. Texas A&M Health Science Center Research Symposium, November 11-12, 2010.

52.  Sarin V, Wu X, Muthuchamy M, and Heaps CL. Exercise training restores contractility in collateral-dependent myocardium independent of calcium sensitization of myofilament proteins. FASEB J. 2010 24:619.21.

53.  Wu X, Meininger GA and Muthuchamy M. Fibronectin Increases Mouse Cardiac Contractility via alpha (5) beta (1) Integrin. Circulation. 2009, 120: S872.

54.  Tong CW, Wu X, Ralphe JC, Scherman JA, Muthuchamy M, Valdivia HH, Moss RL. Cardiac Myosin Binding Protein C Regulates Cross-bridge Kinetics to Affect Diastolic Function. Circulation. 2009, 120: S871 (Top scoring oral abstracts. <30% acceptance rate. Impact factor = 14.8).

55.  Wu X, Trzeciakowski JP, Meininger GA and Muthuchamy M. Mechanical properties of the interaction between fibronectin and integrins on diabetic cardiomyocytes. Circulation. 2008, 118: S_318. (<30% acceptance rate. Impact factor = 14.8, cited by 1)

56.  Muthuchamy M, Dowdie R, Wu X, Zawieja S, Gokulan K, Tong CW, Moss RL. Perturbation of Tropomyosin Amino Acid Residues Binding to Actin at the “Off” State of Tropomyosin Increase Cardiac Muscle Dynamics. Circulation. 2008, 118: S_544.

57.  Tong CW, Wu X, Muthuchamy M, Scherman JA, Valdivia HH, Moss RL. Myosin Binding Protein C is Essential for Beta-adrenergic Mediated Acceleration of Cardiac Relaxation. Circulation, 2008; 118: S_350. (<30% acceptance rate. Impact factor = 14.6, cited by 1)

58.  Tong CW, Wu X, Muthuchamy M, Scherman JA, Valdivia HH, Moss RL. Phosphorylation of Myosin Binding Protein C Contributes to the Force-Frequency Response and Beta-Adrenergic Enhancement of Cardiac Contraction, Circulation, 2008; 118: S_350.

59.  Tong C, Wu X, Muthuchamy M, and Moss R. Ablation of myosin binding protein C accelerates the kinetics of cross-bridge cycling during the myocardial twitch.  Biophys. J. 2008 94: 1444 (Biophysics Meeting, February 2008),

60.  Tong CW, Wu X, Muthuchamy M, Moss RL; Cardiac Myosin Binding Protein-C (cMyBP-C) Phosphorylation Modulates Relaxation in Myocardium, Presented at American Heart Association Basic Cardiovascular Sciences Conference 2008 - Heart Failure: Molecular Mechanisms and Therapeutic Targets, July 28-31 2008, Keystone, CO 2008

61.  Davis MJ, Yang Y, Wu X, Gui P, Sohma Y, Meininger GA, Davis GE, and Braun AP. Potentiation of BK Channels by 5β1 Integrin Activation in Arteriolar Smooth Muscle. FASEB J. 2008 22:1145.3.

62.  Muthuchamy M, Wu X, Sun Z, Trzeciakowskia JP and Meininger GA. Modulation of mechanical properties of the interactions between fibronectin and α5β1-integrin on cardiomyocytes. Journal of Molecular and Cellular Cardiology. 42, Supplement 1, S120-S121, 2007.

63.  Wu X, and Muthuchamy M. Fibronectin increases the force production of mouse papillary muscles via a5b1 integrin. 3rd annual CVRI Research Retreat at Temple, Texas 2007.

64.  Yang Y, Wu X, Wu J et al. Integrin activation results in c-Src mediated phosphorylation and potentiation of Maxi K channels.  FASEB J 2007; 21(5): A538.

65.  Wu X, Sun Z, Trzeciakowski JP, Meininger GA and Muthuchamy M. Mechanical properties of the interaction between fibronectin and α5β1-integrin on cardiomyocytes studied by atomic force microscopy. 2nd annual CVRI Research Retreat at College Station Hilton and Conference Center, 2006, p57.

66.  Hein TW, Razavi HM, Qamirani E, Wu X, Davis MJ, Kuo L. Activation of smooth muscle Kir2.1 channels and Na+/K+ ATPase mediates dilation of coronary arterioles to K+. 2nd annual CVRI Research Retreat at College Station Hilton and Conference Center, 2006, p38.

67.  Wu X, Sun Z, Trzeciakowski JP, Meininger GA and Muthuchamy M. Mechanical properties of the interaction between fibronectin and α5β1-integrin on cardiomyocytes studied by atomic force microscopy. Circulation, 2006, supplement II, 114:II-84.

68.  Wu X, et al.  Regulation of native and heterologously expressed BKCa channels by a5b1 integrin. 2005 FASEB in San Diego, CA; and 1st annual CVRI Research Retreat at Temple, Texas, 2005.

69.  Gui P, Wu X, et al, Mechanosensitivity of heterologously expressed smooth muscle L-type calcium (Cav1.2b).  2005 FASEB in San Diego, CA.

70.  Li J, Wu X, Gui P, et al.  Regulation of L-type Ca2+ channels by a5b1 integrin in native neuronal cells. 2005 FASEB in San Diego, CA.

71.  Wu X, Gui P, Meininger GA, Braun AP, Davis MJ. Regulation of BKCa channels by protein kinases and alpha5beta1 in vascular smooth muscle and HEK cells.  2004 FASEB in Washington DC.

72.  Gui P, Wu X, Ling S, Stotz S, Wilson E, Zamponi GW, Braun AP, Davis GE and Davis MJ. Role of PKA phosphorylation on potentiation of heterologously expressed smooth muscle L-type calcium channels (Cav1.25b) by alpha5beta1 integrin activation. 2004 FASEB in Washington DC.

73.  Gui P, Balasubramanian B, Wu X, Ling S, Stotz S, Wilson E, Zamponi GW, Braun AP, Davis GE and Davis MJ. Effect of α5β1 Integrin Activation on Heterologously Expressed Cardiac L-type Calcium Channels. Biophysics Meeting 2004.

74.  Wu X, et al. Regulation of Ca2+- activated K+ channels by a5b1 integrin. 2003 Biophysics in San Antonio, TX AND 2003 FASEB in San Diego, CA

75.  Gui P, Wu X, et al.  Modulation of Cav1.2 by a5b1 integrin requires PKA and Src phosphorylation of the a1c channel subunit.  2003 Biophysics in San Antonio, TX AND 2003 FASEB in San Diego, CA

76.  Ling S, Gui P, Wu X et al.  Roles for cSrc and protein kinase A in the modulation of L-type Ca2+ channels by integrins.  2003 Biophysics in San Antonio, TX.

77.  Wu X and Davis MJ.  Effects of mechanosensitive ion channel blockers on the vascular myogenic response.  2002 FASEB in New Orleans, LA.

78.  Meininger GA, Martinez-Lemus LA, Sun Z, Trache A, Wu, X et al.  Role of extracellular matrix-integrin interaction in short and long-term responses to pressure.  J Vasc Res, Suppl 1. 2002 European Society for Microcirculation Meeting in Exeter, England.

79.  Wu X, Davis GE, Meininger GA, Wilson E and Davis M.  Role of cytoskeleton and focal adhesion proteins in regulation of vascular smooth muscle L-type calcium channels by a5b1 integrin.  FASEB J, 2001, 15.

80.   Meininger GA, Waitkus-Edwards, KR, Wu X, et al. a4b1 integrin-mediated vasoconstriction of isolated arterioles occurs through activation of L-type calcium channels. 2001 FASEB, Orlando, FL.

81.  Wu X, Davis GE, Wilson E, Meininger GA and Davis M.  Regulation of the L-type calcium channel by avb3 and a5b1 integrins requires signaling between focal adhesion proteins.  2000 FASEB SUMMER RESEARCH CONFERENCES.

82.  Wu X, Davis GE, Meininger GA, Wilson E and Davis M.  Integrin regulation of L-type calcium channels requires signaling between focal adhesion proteins.  FASEB J, 2000, 14(4):A1.

83.  Meininger GA, Platts SH, Wu X, Davis MJ, Davis GE. Integrins and ion channel sin vascular smooth muscle. International Symposium on developments in smooth muscle and endothelial cell signaling. Nagoya, Japan, May, 1999.

84.  Wu X, Davis GE, Meininger GA, Davis MJ. Role of tyrosine kinases in modulation of smooth muscle cell calcium channels by a5b1 integrin ligands. FASEB J 13(4): A45, 1999.

85.  Wu X, Mogford Je, Davis GE, Platts S, Meininger GA and Davis MJ. Modulation of Ca2+ current in arteriolar smooth muscle by avb3 and a5b1 integrin ligands. Molecular Biology of Cell 9:419a-pos2431, 1998.

86.  Wu X and Davis MJ. Stretch-activated cation current in vascular smooth muscle. FASEB J 12(4): A3 (NO.16), 1998.

87.  Wu X, Meininger GA, Platts SH, Davis GE, Mogford JE, Platts SH and Davis MJ. Electrophysiological evidence for integrin modulation of calcium channels in rat arteriolar smooth muscle. Biophysic J 72: A34: M-pos 454, 1997.

88.  Wu X and Davis MJ. Characterization of stretch activated cation current in vascular smooth muscle cells. Microcirculation 4(1): 168, 1997.

89.  Wu X, Mogford JE, Davis GE, Platts S, Meininger GA and Davis MJ. Integrin modulation of calcium channels in rat arteriolar smooth muscle. Microcirculation 4(1): 136, 1997. (cited by 3)

90.  Xin Wu, Mogford JE, Platts SH, Davis GE, Meininger GA and Davis MJ. Integrin-mediated dilation of arterioles in skeletal muscle may involve inhibition of L-type Ca2+ channels. FASEB J 10(3):A54 (NO. 311), 1997.

91.  Xin Wu, Davis MJ, et al. Coronary arteriolar dilation to KCl is mediated by an inwardly rectifying K+ channel in smooth muscle. Microcirculation 3: 110, 1996.

92.  Xin Wu, Mogford JE, Platts SH, Davis GE, Meininger GA and Davis MJ. Integrin-mediated dilation of arterioles in skeletal muscle may involve inhibition of L-type Ca2+ channels. The first Texas A&M University Health Science Center Research Symposium. #68, 1996.

93.  Wu X, et al. Mechanisms of histamine-induced early afterdepolarizations and triggered activity in guinea pig papillary muscles. Abstracts of the Third Congress of Federation of Asian and Oceanian Physiological Societies. Organized by FAOPS, pp 30, Shanghai, China, Nov. 1994.

94.  Wu X, et al. The mechanisms of histamine-induced arrhythmia in guinea-pig ventricular muscle. Proceedings of the XIX Chinese Physiological Conference, Chinese Association for Physiological Sciences, pp 182, Wuhan, China, May 1994.

95.  Huang WQ, Wu X, et al. Early and delayed afterdepolarization induced by cardiac anaphylaxis in guinea pig papillary muscle cells. Proceedings of the XIX Chinese Physiological Conference, Chinese Association for the Physiological Sciences, pp 182, Wuhan, China, May 1994.

96.  Wu X, et al. Mechanisms of early afterdepolarizations and triggered activity in guinea pig papillary muscles induced by histamine. Journal of Chinese Pharmaceutical Sciences 3:172, 1994.

97.  Wu X, et al. Cardiac anaphylaxis-induced early afterdepolarizations and triggered activity in guinea pig papillary muscles. Proceedings of the Third China-Japan Joint Meeting on Pharmacology, Sponsored by Chinese and Japanese Pharmacological Association, pp 133, Beijing, China, May 1993.

98.  Wu X, et al. Induction of early afterdepolarizations and triggered activity by histamine in guinea pig papillary muscle. Proceedings of the Third China-Japan Joint Meeting on Pharmacology, Sponsored by Chinese and Japanese Pharmacological Association, pp 163, Beijing, China, May 1993.

99.  Wu X, et al. Mechanisms of early and delayed afterdepolarization induced by cardiac anaphylaxis. Abstracts of The First Young Physiological Scientist Meeting (CAPS News Communication, supplement), Sponsored by Chinese Association for Physiological Sciences, pp 7, Beijing, China, 1993.

 

Popular Medical Science:

1.      Wu C and Wu X. Number talks: health care, we care. 2010 (online publication).

2.      Wu X. The cardiovascular diseases are the No. 1 killer in USA. Xinmin Evening News (daily) - US Edition, 1997, July 23rd, pp 4.

3.      Wu X. Brief Reviews on 1901-1989 Medical Physiology/Medicine Nobel Prize Award. Acta Acad Med Nantong, 1989, 9(suppl):64.

4.      Wu X. Probe secrets of the human longevity. Longevity, 1990, 54(1):49-50.

5.      Wu X. How to inspect your pulse and respiration. Popular Health, 1989, 4:10.

6.      Wu X. Something about your body temperature. Popular Science on Health, 1988, 5:24.

7.      Wu X. How does food digest through the digestive system? Popular Science on Health, 1988, 5:15.

8.      Wu X. How to inspire medical student with critical thinking. Nantong Medical College Monthly (newspaper). Dec 3, 1985.

 

Other published works

2016.11

Two photographs of Texas A&M Health Science Center published in The Synapse (online Peer-reviewed Newsletter), Texas A&M College of Medicine community

2017.04

Two photographs of Texas A&M Health Science Center published in The Synapse (online Peer-reviewed Newsletter), Texas A&M College of Medicine community

2017.12

Two posts received top 1 and 3 highlights in social networks (App) of American Epilepsy Society Meeting, Dec. 2, 2017

2018.10

Four photographs of Texas A&M Health Science Center published in The Synapse (online Peer-reviewed Newsletter), Texas A&M College of Medicine community

2019.12

Four photographs of Texas A&M Health Science Center published in The Synapse (online Peer-reviewed Newsletter), Texas A&M College of Medicine community