Hung-Jen Wu Research Lab

Chemical Engineering, Texas A&M University

Publications

	Singla, A., Simbassa, S.B., Chirra, B., Gairola, A., Southerland, M.R., Shah, K.N., Rose, R., Chen, Q., Baharat, A., Baez, J., Raina, R., Chapman, M.J., Hassan, A.M., Ivanov, I., Sen, A., Wu, H.-J., Cannon C.L., “Hetero-multivalent targeted liposomal drug delivery to treat Pseudomonas aeruginosa infections”, Vol. 14, 36, 40724–40737, *ACS Applied Materials & Interfaces* (2022) DOI: 10.1021/acsami.2c12943
	2. Gairola, A., Benjamin, A., Weatherston. J.D., Cirillo, J., Wu, H.-J. “Recent development in drug delivery systems for treatment of pulmonary tuberculosis by targeting macrophages: A review”, Vol. 5: 2100193, *Advanced Therapeutics* (2022). DOI: 10.1002/adtp.202100193
	3. Hu, Q., Sellers, C., Kwon, J.S., Wu, H.-J., “Integration of Surface-Enhanced Raman Spectroscopy (SERS) and Machine Learning Tools for Coffee Beverage Classification”, Vol. 3, 100020, *Digital Chemical Engineering*, (2022). DOI: 10.1016/j.dche.2022.100020
	4. Lai, W.-H., Mu, H.‐Y., Lu, Y.‐L., Chen, H., Wen, J.-W., Wu, H.-J., Cheng, C.-M., Huang, J.-H., “Dual-Cell Culture System with Identical Culture Environment for Comparison of Anti-Cancer Drug Toxicity”, Vol. 253, 18, 117555, *Chemical Engineering Science* (2022). DOI: 10.1016/j.ces.2022.117555
	5. Rajil, R., Esmaeili, S., Neuman, B., Nessler, R., Wu, H.-J., Yi, Z., Brick, R., Sokolov, A., Hemmer, P., Scully, M., “Upconversion nanoparticle-based Immunoassay to determine the neutralizing activity of COVID-19 antibodies”, Vol.12: 1263, *Scientific Reports* (2022) DOI: 10.1038/s41598-021-03978-2
	6. Wu, H.-J., Singla, A., Weatherston, J. D. “Nanocube-based fluidic glycan microarray”, *Methods in Molecular Biology: Glycan Microarrays* (Book Chapter) (2022). DOI: 10.1007/978-1-0716-2148-6_4
	7. Lee, D., Green, A., Wu, H.-J., Kwon, J.S., “Hybrid PDE-kMC modeling approach to simulate multivalent lectin-glycan binding process”, Vol. 67(12): e17453, *AIChE* *Journal* (2021) DOI: 10.1002/aic.17453
	8. Zhang, D., Wu, H.-J., Zhou, X., Qi, R., Xua, L., Guo, Y., Liu, X., “Enhanced thermal effect of plasmonic nanostructures confined in discoidal porous silicon particles”, vol. 10, pp 30840-30847, *RSC Advances* (2020). DOI: 10.1039/D0RA03379K
	9. Godara, A., Rodriguez, M.A.G., Weatherston, J.D., Peabody, G., Wu, H.-J., Kao, K., “Beneficial mutations for carotenoids production identified from laboratory-evolved Saccharomyces cerevisiae”, vol. 46, pp 1793-1804, *Journal of Industrial Microbiology & Biotechnology* (2019). DOI: 10.1007/s10295-019-02241-y
	10. Weatherston, J.D., Yuan, S., Mashuga, C.V., Wu, H.-J., " Multi-functional SERS substrate: collection, separation, and identification of airborne chemical powders on a single device", *Sensors and Actuators B: Chemical*, 297, 126765 (2019). DOI: 10.1016/j.snb.2019.126765
	11. Choi H.-K., Lee D., Singla A., Kwon, J.S., Wu, H.-J., "The influence of hetero-multivalency on lectin-glycan binding behavior", *Glycobiology*, 29,397-408 (2019). DOI: 10.1093/glycob/cwz010
	12. Worstell, N.C., Singla, A., Wu, H. J., “Evaluation of Hetero-multivalent Lectin Binding Using a Turbidity-based Emulsion Agglutination Assay”, *Colloids and Surfaces B: Biointerfaces,* 175,84-90 (2019) DOI: 10.1016/j.colsurfb.2018.11.069
	13. Lee D., Mohr, A., Kwon, J. S., Wu, H. J., “Kinetic Monte Carlo modeling of multivalent binding of CTB proteins with GM1 receptors”, *Computers and Chemical Engineering*, 8, 283 (2018) DOI: 10.1016/j.compchemeng.2018.08.011
	14. Lee, D., Singla, A., Wu, H. J., and Kwon, J. S., “An Integrated Numerical and Experimental Framework for Modeling of CTB and GD1b Ganglioside Binding Kinetics”, *AIChE* *Journal*, 64, 3882 (2018). DOI: 10.1002/aic.16209
	15. Worstell, N.C., Singla, A., Saenkham, P., Galbadage, T., Sule, P., Lee, D., Mohr, A., Kwon, J.S., Cirillo, J.D., and Wu, H.-J., “Hetero-Multivalency of Pseudomonas aeruginosa Lectin LecA Binding to Model Membranes”, *Scientific Reports*, 8, 8419 (2018). DOI: 10.1038/s41598-018-26643-7
	16. Lee D., Mohr, A., Kwon, J. S., Wu, H. J., Singla, A., “Stochastic Modelling of CTB-receptor Binding Kinetics”, *Computer Aided Chemical Engineering*, 44, 2143 (2018) DOI: 10.1016/B978-0-444-64241-7.50352-9
	17. Weatherston, J.D., Seguban, R.K.O., Hunt, D., and Wu, H.-J., “Low-cost and simple fabrication of nanoplasmonic paper for coupled chromatography separation and surface enhanced Raman detection”, 3 (4), pp 852–857, *ACS Sensors, (*2018) DOI: 10.1021/acssensors.8b00098
	18. Krishnan, P., Singla, A., Lee, C.-A, Weatherston, J.D., Worstell, N.C., and Wu, H.-J., "Hetero-multivalent binding of Cholera Toxin Subunit B with glycolipid mixtures", *Colloids and Surfaces B: Biointerfaces, vol. 160, 281-288 (2017) [Cover Article*] DOI: 10.1016/j.colsurfb.2017.09.035
	19. Contreras-Naranjo, J.C., Wu, H.-J., Ugaz, V.M., "Microfluidics for exosome isolation and analysis: Enabling liquid biopsy for personalized medicine", *Lab on a Chip*, vol. 17, 3558-3577(2017) DOI: 10.1039/C7LC00592J
	20. Liu, C., Zhao, Z. , Fan, J., Lyon, C.J., Wu, H.-J., Nedelkov, D., Zelazny, A.M., Olivier, K.N., Cazares, L.H., Holland, S.M., Graviss, E.A., Hu, Y., “Quantification of circulating M. tuberculosis antigen peptides allows rapid diagnosis of active disease and treatment monitoring,” *Proceedings of the National Academy of Sciences*, 114 (15) 3969-3974 (2017) See also: News 1 , News 2 , News 3 , News 4
	21. Weatherston, J.D., Worstell, N.C., Wu, H. -J., “Quantitative Surface-Enhanced Raman Spectroscopy (SERS) for Kinetic Analysis of Aldol Condensation Using Ag-Au Core-Shell Nanocube”, *Analyst*, vol. 141, pp. 6051-6060 (2016).
	22. Worstell, N.C., Krishnan, P., Weatherston, J.D., Wu, H. -J., “Binding Cooperativity Matters: A GM1-like Ganglioside-Cholera Toxin B Subunit Binding Study Using a Nanocube-Based Lipid Bilayer Array,” PLOS ONE , 11(4): e0153265 (2016)
	23. Iversen, L., Tu, H-.L., Lin, W.-C, Christensen, S.M., Abel, S.M., Iwig, J., Wu, H.-J., Gureasko, J., Yu, C-.H., Rhodes, C., Petit, R. S., Stamou, D., Chakraborty, A.K., Kuriyan, J., Groves, J.T., “Ras activation by SOS: Allosteric regulation by altered fluctuation dynamics”, vol. 345, pp.50-54, Science. (2014).
	24. Fan, J., Niu, S., Dong, A., Shi, J., Fine, D., Wu, H.-J., Tian, Y. et al., “Nanopore film based enrichment and quantification of low abundance hepcidin from human bodily fluids,” Nanomedicine: Nanotechnology, Biology and Medicine, 10, pp. 879-888. (2014) [Cover Article]. See also: Reported by Science Translational Medicine (Editors' Choice)
	25. Wu, H.-J., Li, Y., Fan, J., Deng, Z., Zhao, H., Graviss, E. A., Liu, X., Ferrari, M., Ma, X., Hu, Y.,“ Antibody-Free Detection of Mycobacterium tuberculosis Antigen Using Customized Nanotraps,” Analytical Chemistry, 86:1988-1996. (2014) See also: Highlighted on Chemical & Engineering News, 2014
	26. Wang, Z., Wu, H.-J., Fine, D., Schmulen, J., Hu, Y., Godin, B., Zhang, J.X., Liu, X., “Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles,” Lab-on-a-chip, 13:2879-2882. (2013)
	27. Fine, D., Grattoni, A., Goodall, R., Wu, H.-J., Srinivasan, S., Ferrari, M., et al., “Silicon Micro- and Nanofabrication for Medicine”, Advanced Healthcare Materials, 2:632-666 (2013). [Cover Article]
	28. Fan, J., Huang, Y., Finoulst, I., Wu, H.-J., Deng, Z., Xu, R., Ferrari, R., Shen, H., Hu, Y., “Serum Biomarkers for Pulmonary Metastatic Melanoma Identified by means of a Nanopore-based Assay,” Cancer Letter, 334: 202-10 (2013).
	29. Wu, H.-J., Henzie, J., Lin, W.-C., Rhodes, C., Li, Z., Thorner, J., Yang, P., Groves, J.T., "Membrane-Protein Binding Measured with Solution-Phase Plasmonic Nanocube Sensors," Nature Methods, 9:1189-91 (2012).
	30. Fan, J., Gallagher, J.W., Wu, H.-J., Landry, M.G., Sakamoto, J., Ferrari, M., Hu, Y., “Low molecular weight protein enrichment on mesoporous silica thin films for biomarker discovery,” Journal of Visualized Experiments, 62:e3876 (2012).
	31. Yu, Y., Fay, N.C., Smoligovets, A., Wu, H.-J., Groves, J.T., "Myosin IIA modulates T cell receptor transport and casl phosphorylation during early immunological synapse formation," PLOS ONE, 7:e30704 (2012).
	32. Smoligovets, A., Wu, H.-J., Smith, A., Petit, R., Groves, J.T., "Characterization of dynamic actin associations with T-cell receptor microclusters in primary T cells," *Journal of Cell Science*, 125:735-42 (2012).
	33. Yu, C., Wu, H.-J., Kaizuka, Y., Vale, R.D., Groves, J.T., "Altered actin centripetal retrograde flow in physically restricted immunological synapses," PLOS ONE, 5(7):e11878 (2010).
	34. Gomez, E.W., Clack, N.G., Wu, H.-J., Groves, J.T., "Like-charge interactions between colloidal particles are asymmetric with respect to sign," Soft Matter, 5:1931-36 (2009).
	35. Wu, H.-J., Shah, S., Beckham, R.E., Meissner, K.E., Bevan, M.A., "Resonant effects in evanescent wave scattering of polydisperse colloids," Langmuir, 24:13790–795 (2008).
	36. Everett, W.N., Wu, H.-J., Anekal, S.G., Bevan, M.A., "Diffusing colloidal probes of protein and synthetic macromolecule interactions," Biophysical Journal, 92:1005-13 (2007).
	37. Wu, H.-J., Everett, W.N., Anekal, S.G., Bevan, M.A., "Mapping patterned potential energy landscapes with diffusing colloidal probes," Langmuir, 22:6826-36 (2006).
	38. Wu, H.-J., Pangburn, T.O., Beckham, R.E., Bevan, M.A., “Measurement and Interpretation of Particle−Particle and Particle−Wall Interactions in Levitated Colloidal Ensembles," Langmuir, 21:9879-88 (2005).
	39. Wu, H.-J., Bevan, M.A., "Direct measurement of single and ensemble average particle-surface potential energy profiles," Langmuir, 21:1244-54 (2005).
	40. Hwang K., Wu, H.-J., Bevan, M.A., "Specific ion-dependent attraction and phase behavior of polymer-coated colloids," Langmuir, 20:11393-401 (2004).