Hung-Jen Wu Research Lab

Chemical Engineering, Texas A&M University

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Publications

          Final published cover (low resolution)  COLSUB_A5_160_cover image    Advanced materia Cover (low resolution)

Google Scholar Entry

1.    Esmaeili, S.; Rajil, N.; Hazrathosseini, A.; Neuman, B.; Alkahtani, M.; Sen, D.; Hu, Q.; Wu, H.-J.; Yi, Z.; Brick, R.; Sokolov, A.; Hemmer, P.R.; Scully, M., “Quantum-Enhanced Detection of Viral cDNA via Luminescence Resonance Energy Transfer Using Upconversion and Gold Nanoparticles”, Nanophotonics. (2025)
DOI: 10.1515/nanoph-2024-0663

2.    Arnob, A.; Gairola, A.; Clayton, H.; Jayaraman, A.; Wu, H.-J., “Factors Promoting Lipopolysaccharide Uptake by Synthetic Lipid Droplets”, Vol. 10, 6, 5866–5873, ACS Omega. (2025), [Supplementary Journal Cover]

DOI: 10.1021/acsomega.4c09599

3.    Hu, Q., Wu, H.-J., “Direct Glycan Analysis of Biological Samples and Intact Glycoproteins by Integrating Machine Learning-Driven Surface-Enhanced Raman Scattering and Boronic Acid Arrays”, Vol. 4, 3, 307-314, ACS Measurement Science Au, (2024) [Journal Cover]

DOI: 10.1021/acsmeasuresciau.4c00014

4.    Hu, Q., Kuai, D., Park, H., Clark, H., Balbuena, P. B., Kwon, J. S., Wu, H.-J., “Advancing Glycan Analysis: A New Platform Integrating SERS, Boronic Acids, and Machine Learning Algorithms”, Advanced Sensor Research (2023). [Inside Cover]

DOI: 10.1002/adsr.202300052

5.    Singla, A., Simbassa, S.B., Chirra, B., Gairola, A., Southerland, M.R., Shah, K.N., Rose, R., Chen, Q., Baharat, A., Baez, J., Raina, R., Chapman, M.J., Hassan, A.M., Ivanov, I., Sen, A., Wu, H.-J., Cannon C.L., “Hetero-multivalent targeted liposomal drug delivery to treat Pseudomonas aeruginosa infections”, Vol. 14, 36, 40724–40737, ACS Applied Materials & Interfaces (2022) [Journal Cover]
DOI: 10.1021/acsami.2c12943

6.    Gairola, A., Benjamin, A., Weatherston. J.D., Cirillo, J., Wu, H.-J. “Recent development in drug delivery systems for treatment of pulmonary tuberculosis by targeting macrophages: A review”, Vol. 5: 2100193, Advanced Therapeutics (2022) [Journal Cover]

DOI: 10.1002/adtp.202100193

7.    Hu, Q., Sellers, C., Kwon, J.S., Wu, H.-J., “Integration of Surface-Enhanced Raman Spectroscopy (SERS) and Machine Learning Tools for Coffee Beverage Classification”, Vol. 3, 100020, Digital Chemical Engineering, (2022).

DOI: 10.1016/j.dche.2022.100020

8.    Lai, W.-H., Mu, H.‐Y., Lu, Y.‐L., Chen, H., Wen, J.-W., Wu, H.-J., Cheng, C.-M., Huang, J.-H., “Dual-Cell Culture System with Identical Culture Environment for Comparison of Anti-Cancer Drug Toxicity”, Vol. 253, 18, 117555, Chemical Engineering Science (2022).

DOI: 10.1016/j.ces.2022.117555

9.    Rajil, R., Esmaeili, S., Neuman, B., Nessler, R., Wu, H.-J., Yi, Z., Brick, R., Sokolov, A., Hemmer, P., Scully, M., “Upconversion nanoparticle-based Immunoassay to determine the neutralizing activity of COVID-19 antibodies”, Vol.12: 1263, Scientific Reports (2022)

DOI: 10.1038/s41598-021-03978-2

10.  Wu, H.-J., Singla, A., Weatherston, J. D. “Nanocube-based fluidic glycan microarray”, Methods in Molecular Biology: Glycan Microarrays (Book Chapter) (2022).

DOI: 10.1007/978-1-0716-2148-6_4

11.  Lee, D., Green, A., Wu, H.-J., Kwon, J.S., “Hybrid PDE-kMC modeling approach to simulate multivalent lectin-glycan binding process”, Vol. 67(12): e17453, AIChE Journal (2021)

DOI: 10.1002/aic.17453

Graphical abstract: Enhanced thermal effect of plasmonic nanostructures confined in discoidal porous silicon particles

12.  Zhang, D., Wu, H.-J., Zhou, X., Qi, R., Xua, L., Guo, Y., Liu, X., “Enhanced thermal effect of plasmonic nanostructures confined in discoidal porous silicon particles”, vol. 10, pp 30840-30847, RSC Advances (2020).

DOI: 10.1039/D0RA03379K

13.  Godara, A., Rodriguez, M.A.G., Weatherston, J.D., Peabody, G., Wu, H.-J., Kao, K., “Beneficial mutations for carotenoids production identified from laboratory-evolved Saccharomyces cerevisiae”, vol. 46, pp 1793-1804, Journal of Industrial Microbiology & Biotechnology (2019).

DOI: 10.1007/s10295-019-02241-y

nanopaper-sample collection-crop

14.  Weatherston, J.D., Yuan, S., Mashuga, C.V., Wu, H.-J., " Multi-functional SERS substrate: collection, separation, and identification of airborne chemical powders on a single device", Sensors and Actuators B: Chemical, 297, 126765 (2019).

DOI: 10.1016/j.snb.2019.126765

Final published cover (low resolution)

15.  Choi H.-K., Lee D., Singla A., Kwon, J.S., Wu, H.-J., "The influence of hetero-multivalency on lectin-glycan binding behavior", Glycobiology, 29,397-408 (2019) [Journal Cover, Editor’s Choice]

DOI: 10.1093/glycob/cwz010

Table of content(low resolution)

16.  Worstell, N.C., Singla, A., Wu, H. J., “Evaluation of Hetero-multivalent Lectin Binding Using a Turbidity-based Emulsion Agglutination Assay”, Colloids and Surfaces B: Biointerfaces, 175,84-90 (2019)

DOI: 10.1016/j.colsurfb.2018.11.069

PIC

17.  Lee D., Mohr, A., Kwon, J. S., Wu, H. J., “Kinetic Monte Carlo modeling of multivalent binding of CTB proteins with GM1 receptors”, Computers and Chemical Engineering, 8, 283 (2018)

DOI: 10.1016/j.compchemeng.2018.08.011

18.  Lee, D., Singla, A., Wu, H. J., and Kwon, J. S., “An Integrated Numerical and Experimental Framework for Modeling of CTB and GD1b Ganglioside Binding Kinetics”, AIChE Journal, 64, 3882 (2018).
DOI: 10.1002/aic.16209

Fig. 1_LecA glycan schematic

19.  Worstell, N.C., Singla, A., Saenkham, P., Galbadage, T., Sule, P., Lee, D., Mohr, A., Kwon, J.S., Cirillo, J.D., and Wu, H.-J., “Hetero-Multivalency of Pseudomonas aeruginosa Lectin LecA Binding to Model Membranes”, Scientific Reports, 8, 8419 (2018).

DOI: 10.1038/s41598-018-26643-7

20.  Lee D., Mohr, A., Kwon, J. S., Wu, H. J., Singla, A., “Stochastic Modelling of CTB-receptor Binding Kinetics”, Computer Aided Chemical Engineering, 44, 2143 (2018)

DOI: 10.1016/B978-0-444-64241-7.50352-9

TOC_1

21.  Weatherston, J.D., Seguban, R.K.O., Hunt, D., and Wu, H.-J., “Low-cost and simple fabrication of nanoplasmonic paper for coupled chromatography separation and surface enhanced Raman detection”, 3 (4), pp 852–857, ACS Sensors,  (2018)

DOI: 10.1021/acssensors.8b00098

COLSUB_A5_160_cover image

22.  Krishnan, P., Singla, A., Lee, C.-A, Weatherston, J.D., Worstell, N.C., and Wu, H.-J., "Hetero-multivalent binding of Cholera Toxin Subunit B with glycolipid mixtures", Colloids and Surfaces B: Biointerfaces, vol. 160, 281-288 (2017) [Journal Cover]

DOI: 10.1016/j.colsurfb.2017.09.035

c7lc00592j-f1

23.  Contreras-Naranjo, J.C., Wu, H.-J., Ugaz, V.M., "Microfluidics for exosome isolation and analysis: Enabling liquid biopsy for personalized medicine", Lab on a Chip, vol. 17, 3558-3577(2017) 

DOI: 10.1039/C7LC00592J

TB diagnosis

24.  Liu, C., Zhao, Z. , Fan, J., Lyon, C.J., Wu, H.-J., Nedelkov, D., Zelazny, A.M., Olivier, K.N., Cazares, L.H., Holland, S.M., Graviss, E.A., Hu, Y., “Quantification of circulating M. tuberculosis antigen peptides allows rapid diagnosis of active disease and treatment monitoring,” Proceedings of the National Academy of Sciences, 114 (15) 3969-3974 (2017)
See also: News 1  ,  News 2  ,  News 3  , News 4

Josh-quantitative Raman

25.  Weatherston, J.D., Worstell, N.C., Wu, H. -J., “Quantitative Surface-Enhanced Raman Spectroscopy (SERS) for Kinetic Analysis of Aldol Condensation Using Ag-Au Core-Shell Nanocube”, Analyst, vol. 141, pp. 6051-6060 (2016).

Nolan-Plos One

26.  Worstell, N.C., Krishnan, P., Weatherston, J.D., Wu, H. -J., “Binding Cooperativity Matters: A GM1-like Ganglioside-Cholera Toxin B Subunit Binding Study Using a Nanocube-Based Lipid Bilayer Array,” PLOS ONE , 11(4): e0153265 (2016)

Ras paper_crop

27.  Iversen, L., Tu, H-.L., Lin, W.-C, Christensen, S.M., Abel, S.M., Iwig, J., Wu, H.-J., Gureasko, J., Yu, C-.H., Rhodes, C., Petit, R. S., Stamou, D., Chakraborty, A.K., Kuriyan, J., Groves, J.T., “Ras activation by SOS: Allosteric regulation by altered fluctuation dynamics”, vol. 345, pp.50-54, Science. (2014).

hepcidin paper cover

28.  Fan, J., Niu, S., Dong, A., Shi, J., Fine, D., Wu, H.-J., Tian, Y. et al., “Nanopore film based enrichment and quantification of low abundance hepcidin from human bodily fluids,” Nanomedicine: Nanotechnology, Biology and Medicine, 10, pp. 879-888. (2014) [Journal Cover]
See also:    Reported by Science Translational Medicine (Editors' Choice)

TB paper

29.  Wu, H.-J., Li, Y., Fan, J., Deng, Z., Zhao, H., Graviss, E. A., Liu, X., Ferrari, M., Ma, X., Hu, Y.,“ Antibody-Free Detection of Mycobacterium tuberculosis Antigen Using Customized Nanotraps,” Analytical Chemistry, 86:1988-1996. (2014)
See also:    Highlighted on Chemical & Engineering News, 2014

Lab-on-a-chip paper

30.  Wang, Z., Wu, H.-J., Fine, D., Schmulen, J., Hu, Y., Godin, B., Zhang, J.X., Liu, X., “Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles,” Lab-on-a-chip, 13:2879-2882. (2013)

Advanced material cover

31.  Fine, D., Grattoni, A., Goodall, R., Wu, H.-J., Srinivasan, S., Ferrari, M., et al., “Silicon Micro- and Nanofabrication for Medicine”, Advanced Healthcare Materials, 2:632-666 (2013). [Journal Cover]

cancer letter

32.  Fan, J., Huang, Y., Finoulst, I., Wu, H.-J., Deng, Z., Xu, R., Ferrari, R., Shen, H., Hu, Y., “Serum Biomarkers for Pulmonary Metastatic Melanoma Identified by means of a Nanopore-based Assay,” Cancer Letter, 334: 202-10 (2013).

nature method_crop

33.  Wu, H.-J., Henzie, J., Lin, W.-C., Rhodes, C., Li, Z., Thorner, J., Yang, P., Groves, J.T., "Membrane-Protein Binding Measured with Solution-Phase Plasmonic Nanocube Sensors," Nature Methods, 9:1189-91 (2012).

JovE

34.  Fan, J., Gallagher, J.W., Wu, H.-J., Landry, M.G., Sakamoto, J., Ferrari, M., Hu, Y., “Low molecular weight protein enrichment on mesoporous silica thin films for biomarker discovery,” Journal of Visualized Experiments, 62:e3876 (2012).

PloS one 2012-2-crop

35.  Yu, Y., Fay, N.C., Smoligovets, A., Wu, H.-J., Groves, J.T., "Myosin IIA modulates T cell receptor transport and casl phosphorylation during early immunological synapse formation," PLOS ONE, 7:e30704 (2012).

J of cell

36.  Smoligovets, A., Wu, H.-J., Smith, A., Petit, R., Groves, J.T., "Characterization of dynamic actin associations with T-cell receptor microclusters in primary T cells," Journal of Cell Science, 125:735-42 (2012).

PloS one 2010

37.  Yu, C., Wu, H.-J., Kaizuka, Y., Vale, R.D., Groves, J.T., "Altered actin centripetal retrograde flow in physically restricted immunological synapses," PLOS ONE, 5(7):e11878 (2010).

soft matter

38.  Gomez, E.W., Clack, N.G., Wu, H.-J., Groves, J.T., "Like-charge interactions between colloidal particles are asymmetric with respect to sign," Soft Matter, 5:1931-36 (2009).

Lamuir 2008

39.  Wu, H.-J., Shah, S., Beckham, R.E., Meissner, K.E., Bevan, M.A., "Resonant effects in evanescent wave scattering of polydisperse colloids," Langmuir, 24:13790–795 (2008).

biophysical journal_crop

40.  Everett, W.N., Wu, H.-J., Anekal, S.G., Bevan, M.A., "Diffusing colloidal probes of protein and synthetic macromolecule interactions," Biophysical Journal, 92:1005-13 (2007).

Langmuir 2006

41.  Wu, H.-J., Everett, W.N., Anekal, S.G., Bevan, M.A., "Mapping patterned potential energy landscapes with diffusing colloidal probes," Langmuir, 22:6826-36 (2006).

Langmuir 2005-2

42.  Wu, H.-J., Pangburn, T.O., Beckham, R.E., Bevan, M.A., “Measurement and Interpretation of Particle−Particle and Particle−Wall Interactions in Levitated Colloidal Ensembles," Langmuir, 21:9879-88 (2005).

Langmuir 2005

43.  Wu, H.-J., Bevan, M.A., "Direct measurement of single and ensemble average particle-surface potential energy profiles," Langmuir, 21:1244-54 (2005).

Langmuir 2004

44.  Hwang K., Wu, H.-J., Bevan, M.A., "Specific ion-dependent attraction and phase behavior of polymer-coated colloids," Langmuir, 20:11393-401 (2004).